AOC Research & Innovation
Our doctors are shaping the future of orthopedics through research and publications that guide the advanced care we provide every day .
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Ability of near infrared spectroscopy to measure oxygenation in isolated upper extremity muscle compartments
Author Dr. Michael S Shuler, et al. Journal The Journal of Hand Surgery, Volume 37 – Issue 2 Summary This study tested near-infrared spectroscopy (NIRS) for monitoring muscle oxygenation in specific forearm compartments during exercise. Researchers found that NIRS values decreased in the actively contracting muscles while resting compartments remained unchanged, demonstrating that NIRS can…
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Near-infrared spectroscopy in acute compartment syndrome
Author Dr. Michael S Shuler, et al. Journal Injury-international Journal of The Care of The Injured, Volume 42 – Issue 12 Summary This study explores a 44-year-old male with a proximal tibia fracture treated with external fixation who developed postoperative hypersensitivity in both legs. Measurements of intramuscular pressures in all compartments of the injured leg…
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Near-infrared spectroscopy in lower extremity trauma
Author Dr. Michael S Shuler, et al. Journal The Journal of Bone & Joint Surgery, Volume 9 – Issue 6 Summary This study explores how near-infrared spectroscopy (NIRS) measures tissue oxygenation after tibial fractures. Researchers found that injured legs showed a consistent increase in oxygenation compared with uninjured legs, and the contralateral limb served effectively…
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Tunnel Convergence in Combined Anterior Cruciate Ligament and Posterolateral Corner Reconstruction
Author Dr. Michael S Shuler, et al. Journal Arthroscopy Journal, Volume 22 – Issue 2 Summary This study examined how different tunnel angles and depths in the lateral femoral condyle affect tunnel collision risk during combined ACL and posterolateral corner reconstruction. Results showed that deeper (30 mm) tunnels and larger axial or coronal angles significantly…
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Risk Factors for Pulmonary Emboli after Total Hip or Knee Arthroplasty
Author Dr. Michael S Shuler, et al. Journal Clinical Orthopaedics and Related Research, Volume 422 Summary This study explores risk factors for pulmonary embolism after total hip or knee arthroplasty. Researchers found that abnormalities in plasminogen activator inhibitor activity, dilute Russell’s viper venom time, prothrombin time, and cholesterol levels were highly predictive of pulmonary embolism,…
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Evaluation of the Validity of the AOFAS Clinical Rating Systems by Correlation to the SF-36
Author Dr. Michael S Shuler, et al. Journal American Orthopaedic Foot & Ankle Society, Volume 100 Summary This study assessed how well the AOFAS Clinical Rating Systems align with the validated SF-36 outcomes measure in 91 patients with foot and ankle conditions. Correlations between the two tools were generally low—ranging from 0.02 to 0.36 overall…
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Angiotensin II Stimulates Calcineurin Activity in Proximal Tubule Epithelia through AT-1 Receptor-Mediated Tyrosine Phosphorylation of the PLC-γ1 Isoform
Author Dr. Michael S Shuler, et al. Journal Journal of the American Society of Nephrology, Volume 13 – Issue 7 Summary This study explores how angiotensin II (AngII) regulates sodium transport in proximal tubule epithelial cells. Researchers found that AngII rapidly activates calcineurin through AT-1 receptor–mediated tyrosine phosphorylation of phospholipase C (PLC), linking AngII signaling…
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